SCHEMBL4632498

SCHEMBL4632498

C=C(C(N)=O)C(C)N1CCOCC1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.39
KDM4E B2RXH2 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
PKM P14618 1/20 0.37
ALDH1A1 P00352 4/20 0.37
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
RAB9A P51151 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
CYP2C19 P33261 1/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 1/20 0.33
GAA P10253 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5799734 0.83 ALDH1A1 (0.41) AAK1SMN1; SMN2PKMALDH1A1MAPT
SCHEMBL6454213 0.82 ALDH1A1 (0.37) KDM4ESMN1; SMN2ALDH1A1KMT2AGAA
SCHEMBL6913113 0.81 MAOB (0.39) KDM4ESMN1; SMN2ALDH1A1KMT2AGAA
SCHEMBL2129974 0.80 AAK1 (0.42) AAK1KDM4ESMN1; SMN2PKMALDH1A1
SCHEMBL2715770 0.80 AAK1 (0.42) AAK1KDM4ESMN1; SMN2PKMALDH1A1
Water SCHEMBL29947214 0.79 AAK1 (0.41) AAK1KDM4ESMN1; SMN2PKMALDH1A1
Water SCHEMBL29902298 0.79 AAK1 (0.41) AAK1KDM4ESMN1; SMN2PKMALDH1A1
SCHEMBL8902371 0.78 SMN1; SMN2 (0.42) AAK1KDM4ESMN1; SMN2PKMALDH1A1
SCHEMBL11797800 0.77 ALDH1A1 (0.41) KDM4ESMN1; SMN2ALDH1A1MAPTKMT2A
SCHEMBL15711018 0.76 AAK1 (0.41) AAK1KDM4ESMN1; SMN2PKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP claimed
EP-1504044-A2 CORE-SHELL POLYMERIC COMPOSITIONS MEADWESTVACO CORPORATION, Law Department (US) 2005-02-09 EP claimed
US-6767638-B2 Core-shell polymeric compositions MEADWESTVACO CORPORATION 2004-07-27 US claimed
WO-2004011513-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-02-05 WO claimed
WO-2003097709-A2 CORE-SHELL POLYMERIC COMPOSITIONS MEADWESTVACO CORPORATION (US) 2003-11-27 WO claimed
US-20030215604-A1 Core-shell polymeric compositions WESTVACO CORPORATION (US) 2003-11-20 US claimed
EP-0296926-B1 COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1992-10-14 EP claimed
US-5075371-A COMPOSITE POLYMERS AND THEIR PREPARATION WHICH ARE USEFUL IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-12-24 US claimed
US-5053135-A COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-10-01 US claimed
EP-0296926-A1 Composite polymers, their preparation and their use in liquid chromatography I.B.F. (FR) 1988-12-28 EP claimed
US-20250073647-A1 DIETHYLAMINO ETHYL POLYMERS AND METHODS OF USE CYTIVA US LLC 2025-03-06 US disclosed
WO-2025049117-A1 DIETHYLAMINO ETHYL POLYMERS AND METHODS OF USE CYTIVA US LLC (US) 2025-03-06 WO disclosed
EP-1927889-A1 Lithographic printing plate precursor FUJIFILM Corporation (JP) 2008-06-04 EP disclosed
EP-1539846-A1 GRAFT COPOLYMERS, THEIR PREPARATION AND USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2005-06-15 EP disclosed
EP-1504044-A2 CORE-SHELL POLYMERIC COMPOSITIONS MEADWESTVACO CORPORATION, Law Department (US) 2005-02-09 EP disclosed
US-5133970-A WATER-SOLUBLE PRESSURE-SENSITIVE SKIN-ADHESIVE AND USE THEREOF ROHM GMBH CHEMISCHE FABRIK (DE) 1992-07-28 US disclosed
US-5075371-A COMPOSITE POLYMERS AND THEIR PREPARATION WHICH ARE USEFUL IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-12-24 US disclosed
US-5053135-A COMPOSITE POLYMERS, THEIR PREPARATION AND THEIR USE IN LIQUID CHROMATOGRAPHY I.B.F. (FR) 1991-10-01 US disclosed
US-4686166-A HIGH IMAGE DENSITY, ANTIFOGGING AGENT HITACHI CHEMICAL CO. (JP) 1987-08-11 US disclosed
US-3957492-A Photographic silver halide emulsion comprising an amphoteric copolymer FUJI PHOTO FILM CO., LTD. (JA) 1976-05-18 US disclosed