Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPMT | P51580 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.31 |
| ▸ | GAA | P10253 | 6/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | GFER | P55789 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.31 |
| ▸ | PLEC | Q15149 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633318 | 0.85 | MAP4K1 (0.34) | ALDH1A1 | |
| SCHEMBL21820432 | 0.67 | ABL1 (0.55) | — | |
| SCHEMBL31159734 | 0.66 | PPARG (0.36) | HTTKDM4EMAPTNPC1 | |
| SCHEMBL988442 | 0.64 | TPMT (0.54) | TPMTHSD17B10HTTKDM4EGAA | |
| SCHEMBL20916711 | 0.64 | RORC (0.43) | HSD17B10KDM4EMAPTALDH1A1NPC1 | |
| SCHEMBL10487792 | 0.62 | MAPT (0.54) | TPMTHSD17B10KDM4EGAAMAPT | |
| SCHEMBL18247596 | 0.62 | TDP1 (0.53) | HSD17B10HTTKDM4EGAAMAPT | |
| SCHEMBL31325823 | 0.61 | SRC (0.36) | TPMTALOX15TSHRHIF1AKDM4E | |
| SCHEMBL3252847 | 0.60 | KDM4E (0.48) | TPMTHSD17B10ALOX15TSHRHTT | |
| SCHEMBL1509519 | 0.60 | KDM4E (0.48) | TPMTHSD17B10ALOX15TSHRHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926714-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | Nycomed GmbH (DE) | 2008-06-04 | — | — | EP | disclosed |
| WO-2007023135-A1 | ISOTOPICALLY SUBSTITUTED BENZIMIDAZOLE DERIVATIVES | NYCOMED GMBH (DE) | 2007-03-01 | — | — | WO | disclosed |