Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 12/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.31 |
| ▸ | HTR3B | O95264 | 1/20 | 0.31 |
| ▸ | HTR3A | P46098 | 1/20 | 0.31 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.31 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RAD52 | P43351 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17813497 | 0.84 | GRM5 (0.34) | GRM5APPKDM4EALDH1A1ATM | |
| SCHEMBL2669115 | 0.78 | GRM5 (0.39) | GRM5 | |
| SCHEMBL18563799 | 0.74 | CYP2C19 (0.40) | GRM5KDM4EALDH1A1 | |
| SCHEMBL16664389 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1 | |
| SCHEMBL256367 | 0.72 | GRM5 (0.33) | GRM5KDM4EALDH1A1 | |
| SCHEMBL6127832 | 0.68 | HTR3E (0.34) | GRM5ALDH1A1HTR3EHTR3BHTR3A | |
| SCHEMBL24675075 | 0.68 | HTR2A (0.43) | ALDH1A1HTR3A | |
| SCHEMBL24675062 | 0.68 | HTR2A (0.43) | ALDH1A1HTR3A | |
| SCHEMBL2669107 | 0.67 | GRM5 (0.58) | GRM5 | |
| SCHEMBL17813500 | 0.67 | GRM5 (0.40) | GRM5APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011151436-A2 | NOVEL COMPOUNDS, METHOD FOR USE THEM AND PHARMACEUTICAL COMPOSITION CONTAINING THEM | EUROSCREEN S.A. (BE) | 2011-12-08 | — | — | WO | disclosed |