⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4518471 | 0.77 | — | — | |
| SCHEMBL17472507 | 0.76 | — | — | |
| SCHEMBL17136898 | 0.71 | — | — | |
| SCHEMBL14750173 | 0.71 | — | — | |
| SCHEMBL332372 | 0.71 | — | — | |
| SCHEMBL25367156 | 0.65 | MEN1 (0.37) | — | |
| SCHEMBL25365743 | 0.65 | ALDH1A1 (0.36) | — | |
| SCHEMBL25366852 | 0.65 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL14308799 | 0.62 | — | — | |
| SCHEMBL14308787 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080242838-A1 | LABELING REAGENT AND METHODS OF USE | IRM LLC (BM) | 2008-10-02 | — | — | US | disclosed |
| EP-1930335-A1 | Cephalosporines having cyclic aminoguanidine substituents as Antibiotics | Nabriva Therapeutics AG (AT) | 2008-06-11 | — | — | EP | disclosed |
| US-6440957-B1 | Cephalosporines having cyclic aminoguanidine substituents as antibiotics | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2002-08-27 | — | — | US | disclosed |
| EP-1082326-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999048896-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1999-09-30 | — | — | WO | disclosed |