Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | HTR1D | P28221 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | HTR1B | P28222 | 1/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | HTR7 | P34969 | 1/20 | 0.52 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.52 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4632750 | 0.88 | HTR2A (0.60) | HTR2AMEN1KMT2AHTR1DHTR6 | |
| SCHEMBL3185761 | 0.86 | HTR2A (0.64) | HTR2AMEN1KMT2AHTR1DHTR6 | |
| SCHEMBL3183193 | 0.84 | HTR2A (0.43) | HTR2AMEN1KMT2AHTR6MAPT | |
| SCHEMBL4633493 | 0.84 | HTR2A (0.54) | HTR2AMEN1KMT2AHTR1DHTR2C | |
| SCHEMBL4633098 | 0.84 | HTR2A (0.58) | HTR2AMEN1KMT2AHTR1DHTR1A | |
| SCHEMBL4633963 | 0.84 | HTR2A (0.54) | HTR2AMEN1KMT2AHTR1DHTR2C | |
| SCHEMBL1399403 | 0.82 | HTR2A (0.55) | HTR2AHTR1DHTR6MAPTCYP1A2 | |
| SCHEMBL4632198 | 0.81 | HTR2A (0.58) | HTR2AMEN1KMT2AHTR1DHTR1A | |
| SCHEMBL4632792 | 0.81 | HTR2A (0.60) | HTR2AMEN1KMT2AHTR1DHTR6 | |
| SCHEMBL1399265 | 0.79 | HTR2A (0.60) | HTR2AMEN1KMT2AHTR1DHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701940-B1 | 2-(1H-INDOLYLSULFANYL)-BENZYL AMINE DERIVATIVES AS SSRI | LUNDBECK & CO AS H (DK) | 2008-05-28 | — | — | EP | claimed |