⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13675690 | 1.00 | — | — | |
| SCHEMBL1767791 | 0.69 | — | — | |
| SCHEMBL11946108 | 0.69 | — | — | |
| SCHEMBL15336485 | 0.69 | — | — | |
| SCHEMBL11624372 | 0.69 | — | — | |
| SCHEMBL999515 | 0.69 | — | — | |
| SCHEMBL620843 | 0.69 | — | — | |
| SCHEMBL13850734 | 0.69 | — | — | |
| SCHEMBL1286918 | 0.69 | — | — | |
| SCHEMBL14508108 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1930335-A1 | Cephalosporines having cyclic aminoguanidine substituents as Antibiotics | Nabriva Therapeutics AG (AT) | 2008-06-11 | — | — | EP | disclosed |
| US-6440957-B1 | Cephalosporines having cyclic aminoguanidine substituents as antibiotics | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2002-08-27 | — | — | US | disclosed |
| EP-1082326-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE Gesellschaft m.b.H. (AT) | 2001-03-14 | — | — | EP | disclosed |
| WO-1999048896-A1 | CEPHALOSPORINES HAVING CYCLIC AMINOGUANIDINE SUBSTITUENTS AS ANTIBIOTICS | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1999-09-30 | — | — | WO | disclosed |
| US-4226852-A | ALKALINITY, AMMONIA-FREE, GUANIDINE DERIVATIVE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1980-10-07 | — | — | US | disclosed |
| US-4186186-A | Guanidine accelerators for peroxide hair bleaching compositions | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 1980-01-29 | — | — | US | disclosed |