SCHEMBL4633192

SCHEMBL4633192

Clc1ccnc(-c2ccccn2)c1Cl.[Pd]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.48
CCR1 P32246 3/20 0.48
CCR5 P51681 3/20 0.48
CCR8 P51685 3/20 0.48
LMNA P02545 3/20 0.48
CYP1A2 P05177 1/20 0.48
POLB P06746 1/20 0.48
METAP1 P53582 1/20 0.48
BLM P54132 1/20 0.48
HIF1A Q16665 1/20 0.48
DOHH Q9BU89 1/20 0.48
P4HTM Q9NXG6 1/20 0.48
NPC1 O15118 4/20 0.42
TP53 P04637 3/20 0.42
TDP1 Q9NUW8 3/20 0.42
RAB9A P51151 3/20 0.42
ALOX15 P16050 2/20 0.42
HTT P42858 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2306242 0.98 KDM4E (0.50) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL31397781 0.96 KDM4E (0.48) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL28201148 0.96 KDM4E (0.48) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL6307849 0.96 KDM4E (0.48) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL4291896 0.84 KDM4E (0.58) KDM4ECCR1CCR5CCR8LMNA
Water SCHEMBL5448516 0.83 KDM4E (0.56) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL7553182 0.82 KDM4E (0.50) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL4782261 0.79 KDM4E (0.49) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL2507724 0.78 KDM4E (0.54) KDM4ECCR1CCR5CCR8LMNA
SCHEMBL28700586 0.77 KDM4E (0.48) KDM4ECCR1CCR5CCR8LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118994260-A Tetrahydronaphthol-phosphine late transition metal complex, and preparation method and application thereof 中国石油化工股份有限公司 2024-11-22 CN claimed
CN-118994261-A Aryl-containing substituted tetrahydronaphthol-phosphine complex and preparation method and application thereof 中国石油化工股份有限公司 2024-11-22 CN claimed
CN-118620001-A Metal organic complex and preparation method and application thereof 中国石油化工股份有限公司 2024-09-10 CN claimed
CN-117903208-A Phosphine-phenol post-transition metal complex, preparation method and application thereof 中国石油化工股份有限公司 2024-04-19 CN claimed
CN-119798493-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-04-11 CN disclosed
CN-119661749-A Coordination precipitation polymerization process for olefin polymerization and polyolefin 中国石油化工股份有限公司 2025-03-21 CN disclosed
CN-118994260-A Tetrahydronaphthol-phosphine late transition metal complex, and preparation method and application thereof 中国石油化工股份有限公司 2024-11-22 CN disclosed
CN-118994261-A Aryl-containing substituted tetrahydronaphthol-phosphine complex and preparation method and application thereof 中国石油化工股份有限公司 2024-11-22 CN disclosed
CN-118620001-A Metal organic complex and preparation method and application thereof 中国石油化工股份有限公司 2024-09-10 CN disclosed
CN-103949263-B For the perovskite mixed oxides catalyst and preparation method thereof of methane methyl alcohol NORTHEAST PETROLEUM UNIVERSITY (CN) 2016-04-13 CN disclosed
CN-103962142-A Preparation method for core-shell perovskite-type catalyst for preparing methanol through methane UNIV NORTHEAST PETROLEUM 2014-08-06 CN disclosed
CN-103949263-A Perovskite composite oxide catalyst for preparing methyl alcohol from methane as well as preparation method of catalyst UNIV NORTHEAST PETROLEUM 2014-07-30 CN disclosed
EP-1930329-B1 1,3,5-TRIAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME AS COMPONENT TOSOH CORP (JP) 2012-10-24 EP disclosed
EP-1930329-A1 1,3,5-TRIAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, AND ORGANIC ELECTROLUMINESCENT DEVICE CONTAINING SAME AS COMPONENT Tosoh Corporation (JP) 2008-06-11 EP disclosed
EP-0698605-B1 Thiophene derivatives and polymers thereof JAPAN RES DEV CORP (JP) 2001-11-21 EP disclosed
US-5734065-A Thiophene derivative and the polymer thereof and methods for production thereof RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1998-03-31 US disclosed
EP-0698605-A1 Thiophene derivatives and polymers thereof RESEARCH DEVELOPMENT CORPORATION OF JAPAN (JP) 1996-02-28 EP disclosed