Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTK | P33981 | 12/20 | 0.53 |
| ▸ | FYN | P06241 | 3/20 | 0.46 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | ERN1 | O75460 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15559752 | 0.88 | TTK (0.55) | TTKFYNERN1 | |
| SCHEMBL10279180 | 0.87 | TTK (0.56) | TTKFYNMKNK1ERN1 | |
| SCHEMBL10279181 | 0.86 | TTK (0.59) | TTKFYNMKNK1ERN1 | |
| SCHEMBL10279183 | 0.85 | TTK (0.58) | TTKFYNMKNK1 | |
| SCHEMBL104538 | 0.82 | TTK (0.77) | TTK | |
| SCHEMBL470209 | 0.81 | TTK (0.56) | TTKFYNMKNK1ERN1 | |
| SCHEMBL463339 | 0.78 | TTK (0.48) | TTKFYNMKNK1ERN1 | |
| SCHEMBL470132 | 0.76 | TTK (0.46) | TTKFYNIKBKBERN1 | |
| SCHEMBL470013 | 0.76 | CYP1A2 (0.54) | TTKFYNIKBKB | |
| SCHEMBL462985 | 0.76 | TTK (0.64) | TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014020041-A1 | COMBINATIONS FOR THE TREATMENT OF CANCER | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2014-02-06 | — | — | WO | claimed |
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | claimed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | claimed |