Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.58 |
| ▸ | MRGPRX4 | Q96LA9 | 7/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.45 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLC26A4 | O43511 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3194387 | 0.90 | FABP3 (0.60) | FABP3FABP4FABP5MRGPRX4HDAC8 | |
| SCHEMBL3194755 | 0.83 | PTGER3 (0.45) | FABP3FABP4FABP5MRGPRX4HDAC8 | |
| SCHEMBL3194736 | 0.83 | PTGER3 (0.45) | FABP3FABP4FABP5MRGPRX4HDAC8 | |
| SCHEMBL3221047 | 0.80 | FABP3 (0.47) | FABP3FABP4FABP5MRGPRX4HDAC8 | |
| SCHEMBL3210788 | 0.77 | FABP3 (0.44) | FABP3FABP4FABP5MRGPRX4HDAC8 | |
| SCHEMBL1505166 | 0.76 | GAA (0.60) | MRGPRX4PTGER1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL19859014 | 0.76 | TSHR (0.47) | MRGPRX4ALDH1A1GAAKDM4CKMT2A | |
| SCHEMBL5839536 | 0.74 | FABP4 (1.00) | FABP3FABP4FABP5MRGPRX4HDAC8 | |
| SCHEMBL3198974 | 0.73 | PTGER3 (0.46) | FABP3FABP4FABP5MRGPRX4HDAC8 | |
| SCHEMBL3198991 | 0.73 | PTGER3 (0.46) | FABP3FABP4FABP5MRGPRX4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912645-A2 | THERAPEUTIC AGENT FOR DIABETES | Takeda Pharmaceutical Company Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007018314-A2 | THERAPEUTIC AGENT FOR DIABETES | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-15 | — | — | WO | disclosed |