Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5711637 | 1.00 | MEN1 (0.40) | MEN1KMT2APARP1USP2MAPT | |
| Bromide SCHEMBL3890946 | 0.99 | MEN1 (0.39) | MEN1KMT2APARP1USP2MAPT | |
| Bromide SCHEMBL3890949 | 0.99 | MEN1 (0.39) | MEN1KMT2APARP1USP2MAPT | |
| Bromide SCHEMBL4534732 | 0.86 | MEN1 (0.41) | MEN1KMT2AUSP2MAPTPOLB | |
| Bromide SCHEMBL4532718 | 0.86 | MEN1 (0.41) | MEN1KMT2AUSP2MAPTPOLB | |
| SCHEMBL9010771 | 0.81 | MAPT (0.49) | MEN1KMT2APARP1USP2MAPT | |
| SCHEMBL3905741 | 0.78 | CISD1 (0.46) | MEN1KMT2APARP1USP2MAPT | |
| SCHEMBL3890952 | 0.78 | CISD1 (0.46) | MEN1KMT2APARP1USP2MAPT | |
| Bromide SCHEMBL4535352 | 0.77 | KMT2A (0.42) | MEN1KMT2AUSP2MAPTPOLB | |
| Bromide SCHEMBL4535340 | 0.77 | KMT2A (0.42) | MEN1KMT2AUSP2MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1729723-B1 | NEUTRAL AND CATIONIC NAPHTHALENE DERIVATIVES AND DYES CONTAINING SAID COMPOUNDS FOR DYEING KERATIN FIBERS | WELLA AG (DE) | 2008-06-04 | — | — | EP | claimed |
| EP-1720513-A1 | LIGHTENING DIRECT DYESTUFFS FOR KERATIN FIBERS AND DYES CONTAINING SAID COMPOUNDS | Wella Aktiengesellschaft (DE) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005074872-A1 | LIGHTENING DIRECT DYESTUFFS FOR KERATIN FIBERS AND DYES CONTAINING SAID COMPOUNDS | WELLA AKTIENGESELLSCHAFT (DE) | 2005-08-18 | — | — | WO | disclosed |