SCHEMBL4633987

SCHEMBL4633987

C=CC(N)n1cnc2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.50
HPGD P15428 1/20 0.50
KMT2A Q03164 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TDP1 Q9NUW8 1/20 0.42
HTT P42858 2/20 0.41
HDAC8 Q9BY41 1/20 0.40
MKNK1 Q9BUB5 1/20 0.40
MKNK2 Q9HBH9 1/20 0.40
POLB P06746 1/20 0.38
TNF P01375 1/20 0.38
CYP11B1 P15538 1/20 0.38
CYP11B2 P19099 1/20 0.38
FGFR1 P11362 1/20 0.37
ROCK1 Q13464 1/20 0.36
LMNA P02545 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
STAT6 P42226 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8025717 0.83 MEN1 (0.54) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL9697193 0.79 HSD17B10 (0.50) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL9165313 0.79 MEN1 (0.58) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL5884242 0.79 HSD17B10 (0.50) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL8912868 0.77 HSD17B10 (0.59) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL630931 0.77 MEN1 (0.64) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL9500071 0.74 HDAC8 (0.54) MEN1HPGDKMT2AHSD17B10TDP1
Hydrochloric Acid SCHEMBL9787788 0.74 HPGD (0.66) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL7814340 0.73 MEN1 (0.54) MEN1HPGDKMT2AHSD17B10TDP1
SCHEMBL9754107 0.73 HSD17B10 (0.54) MEN1HPGDKMT2AHSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2468530-B1 Pneumatic tyres for a vehicle CONTINENTAL REIFEN DEUTSCHLAND (DE) 2014-02-26 EP claimed
WO-2012084345-A1 PNEUMATIC TIRE FOR VEHICLES CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2012-06-28 WO claimed
EP-2468530-A1 Pneumatic tyres for a vehicle Continental Reifen Deutschland GmbH (DE) 2012-06-27 EP claimed
EP-1657320-A1 Fluid and its use to prepare iron and steel based mixtures Zschimmer & Schwarz GmbH & Co KG Chemische Fabriken (DE) 2006-05-17 EP claimed
WO-1992022686-A1 METHOD OF PRETREATING THE SURFACES OF NON-FERROUS METALS PRIOR TO GALVANIC DEPOSITION OF A COAT OF METAL HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1992-12-23 WO claimed
WO-2015161842-A1 AFTER-CLEANING METHOD FOR METALLIC CONTACT ELEMENTS HARTING KGAA (DE) 2015-10-29 WO disclosed
EP-2468530-B1 Pneumatic tyres for a vehicle CONTINENTAL REIFEN DEUTSCHLAND (DE) 2014-02-26 EP disclosed
WO-2012084345-A1 PNEUMATIC TIRE FOR VEHICLES CONTINENTAL REIFEN DEUTSCHLAND GMBH (DE) 2012-06-28 WO disclosed
EP-2468530-A1 Pneumatic tyres for a vehicle Continental Reifen Deutschland GmbH (DE) 2012-06-27 EP disclosed
EP-1657320-B1 Use of a fluid to prepare iron and steel based mixtures ZSCHIMMER & SCHWARZ GMBH & CO (DE) 2008-02-27 EP disclosed
EP-1657320-A1 Fluid and its use to prepare iron and steel based mixtures Zschimmer & Schwarz GmbH & Co KG Chemische Fabriken (DE) 2006-05-17 EP disclosed
US-5086092-A Good paint adhesion BASF LACKE+FARBEN AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed