Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865198 | 0.78 | MEN1 (0.69) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL4633987 | 0.77 | MEN1 (0.50) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL9697193 | 0.77 | HSD17B10 (0.50) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL9165313 | 0.77 | MEN1 (0.58) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL5884242 | 0.77 | HSD17B10 (0.50) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL3694897 | 0.77 | HSD17B10 (0.42) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL9500071 | 0.75 | HDAC8 (0.54) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL6949717 | 0.75 | CYP17A1 (0.38) | HSD17B10MEN1HPGDKMT2ACYP17A1 | |
| SCHEMBL3304570 | 0.75 | MEN1 (1.00) | HSD17B10MEN1HPGDKMT2AHTT | |
| SCHEMBL15540388 | 0.75 | MEN1 (1.00) | HSD17B10MEN1HPGDKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0654474-B1 | Benzimidazole dimers and their use as charge stabilizers | BASF AG (DE) | 1997-01-29 | — | — | EP | disclosed |
| US-5478940-A | Double benzimidazoles | BASF AKTIENGESELLSCHAFT (DE) | 1995-12-26 | — | — | US | disclosed |
| EP-0654474-A1 | Benzimidazole dimers and their use as charge stabilizers | BASF AKTIENGESELLSCHAFT (DE) | 1995-05-24 | — | — | EP | disclosed |
| US-4663339-A | Acaricidal and insecticidal substituted 1-phenylalkylbenzimidazoles | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-05-05 | — | — | US | disclosed |