Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4246626 | 0.94 | — | — | |
| SCHEMBL16613161 | 0.92 | — | — | |
| SCHEMBL28229906 | 0.72 | — | — | |
| SCHEMBL6008386 | 0.71 | — | — | |
| SCHEMBL6008262 | 0.70 | — | — | |
| SCHEMBL9063271 | 0.69 | — | — | |
| SCHEMBL8031306 | 0.69 | — | — | |
| SCHEMBL3264670 | 0.69 | — | — | |
| SCHEMBL3268405 | 0.68 | — | — | |
| SCHEMBL9116773 | 0.68 | GPR84 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043161-A | Methods and pharmaceutical compositions for treating diseases | 苏州同力生物医药有限公司 | 2023-11-10 | — | — | CN | disclosed |
| EP-3493808-A2 | PHARMACEUTICAL COMPOSITIONS OF IBRUTINIB | Cipla Limited (IN) | 2019-06-12 | — | — | EP | disclosed |
| WO-2018033941-A2 | PHARMACEUTICAL COMPOSITIONS OF IBRUTINIB | CIPLA LIMITED (IN) | 2018-02-22 | — | — | WO | disclosed |
| WO-2015145157-A1 | PHARMACEUTICAL COMPOSITION COMPRISING PAZOPANIB | CIPLA LIMITED (IN) | 2015-10-01 | — | — | WO | disclosed |
| WO-2015145145-A1 | PHARMACEUTICAL COMPOSITION COMPRISING LAPATINIB | CIPLA LIMITED (IN) | 2015-10-01 | — | — | WO | disclosed |
| WO-2015140569-A1 | PHARMACEUTICAL COMPOSITION | CIPLA LIMITED (IN) | 2015-09-24 | — | — | WO | disclosed |
| WO-2015136294-A1 | PHARMACEUTICAL COMPOSITTION COMPRISING RILPIVIRINE | CIPLA LIMITED (IN) | 2015-09-17 | — | — | WO | disclosed |
| WO-2015114314-A1 | PHARMACEUTICAL COMPOSITION COMPRISING ABIRATERONE | CIPLA LIMITED (IN) | 2015-08-06 | — | — | WO | disclosed |
| WO-2015071668-A1 | PHARMACEUTICAL COMPOSITIONS | CIPLA LIMITED (IN) | 2015-05-21 | — | — | WO | disclosed |
| WO-2014199131-A1 | Fixed Dose Pharmaceutical Composition | CIPLA LIMITED (IN) | 2014-12-18 | — | — | WO | disclosed |
| WO-2012010854-A1 | INHALATION FORMULATIONS COMPRISING CARMOTEROL IN COMBINATION WITH A CORTICOSTEROID | CIPLA LIMITED (IN) | 2012-01-26 | — | — | WO | disclosed |