Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL455478 | 0.82 | KDM4E (0.78) | KDM4EALDH1A1GAAGLAHTT | |
| Hydrochloric Acid SCHEMBL2834512 | 0.81 | KDM4E (0.77) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL2833037 | 0.80 | KDM4E (0.72) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL2834358 | 0.76 | KDM4E (0.65) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL9685620 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL455004 | 0.75 | KDM4E (0.55) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL2834517 | 0.74 | KDM4E (0.63) | KDM4EALDH1A1GAAGLAHTT | |
| Hydrochloric Acid SCHEMBL2832644 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL457100 | 0.74 | KDM4E (0.83) | KDM4EALDH1A1GAAGLAHTT | |
| SCHEMBL9685162 | 0.73 | KDM4E (0.86) | KDM4EALDH1A1GAAGLAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121345-A1 | NOVEL COMBINATION AND USE | HELPERBY THERAPEUTICS LIMITED (GB) | 2011-10-06 | — | — | WO | claimed |