Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 10/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 10/20 | 0.50 |
| ▸ | S1PR4 | O95977 | 7/20 | 0.50 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.50 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4633536 | 1.00 | S1PR1 (0.50) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL4633537 | 1.00 | S1PR1 (0.50) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL4634589 | 0.93 | S1PR1 (0.45) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| Hydrochloric Acid SCHEMBL4665136 | 0.92 | S1PR1 (0.44) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL4633518 | 0.88 | S1PR5 (0.47) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4633616 | 0.88 | S1PR5 (0.47) | S1PR1S1PR3S1PR5 | |
| Hydrochloric Acid SCHEMBL4634609 | 0.87 | S1PR5 (0.46) | S1PR1S1PR3S1PR5 | |
| SCHEMBL4634092 | 0.84 | NAAA (0.42) | S1PR1S1PR3S1PR5ALDH1A1 | |
| SCHEMBL4296871 | 0.84 | S1PR1 (0.52) | S1PR1S1PR3S1PR4S1PR5S1PR2 | |
| SCHEMBL4291859 | 0.84 | S1PR1 (0.52) | S1PR1S1PR3S1PR4S1PR5S1PR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650186-B1 | Novel dicarboxylic acid derivatives | BIOPROJET SOC CIV (FR) | 2008-06-04 | — | — | EP | claimed |