Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 7/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19466474 | 0.83 | — | — | |
| SCHEMBL6327778 | 0.82 | DRD3 (0.32) | DRD3 | |
| SCHEMBL19466478 | 0.77 | DRD3 (0.31) | DRD3 | |
| SCHEMBL28134274 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1DRD3SLC18A3MAPK1 | |
| SCHEMBL12331468 | 0.76 | KDM4E (0.45) | KDM4EALDH1A1DRD3SLC18A3MAPK1 | |
| SCHEMBL6043875 | 0.76 | KDM1A (0.47) | KDM4EALDH1A1DRD3SLC18A3MAPK1 | |
| SCHEMBL11392579 | 0.75 | — | — | |
| SCHEMBL11213803 | 0.75 | — | — | |
| SCHEMBL13337770 | 0.74 | KDM4E (0.44) | KDM4EALDH1A1DRD3SLC18A3MAPK1 | |
| SCHEMBL27814512 | 0.74 | EBP (0.47) | DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934182-A1 | N-SUBSTITUTED PYRIDINONE OR PYRIMIDINONE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007044491-A1 | N-SUBSTITUTED PYRIDINONE OR PYRIMIDINONE COMPOUNDS USEFUL AS SOLUBLE EPOXIDE HYDROLASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-19 | — | — | WO | disclosed |