SCHEMBL6327778

SCHEMBL6327778

ClCCN1CCOC(Cl)C1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4634683 0.82 KDM4E (0.45) DRD3
SCHEMBL11392579 0.77
SCHEMBL19466474 0.77
SCHEMBL11213803 0.77
SCHEMBL27814512 0.76 EBP (0.47) DRD3
Hydrochloric Acid SCHEMBL3131967 0.75 DRD4 (0.43) DRD3
SCHEMBL1828412 0.74
SCHEMBL19466478 0.74 DRD3 (0.31) DRD3
SCHEMBL8656820 0.72
SCHEMBL20570593 0.72 DRD3 (0.30) DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers KOMOSCHINSKI JOACHIM 2005-11-24 US disclosed
US-6964963-B2 Preparation of 4-amino-1-naphthol ethers BAYER AKTIENGESELLSCHAFT (DE) 2005-11-15 US disclosed
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers LANXESS DEUTSCHLAND GMBH (DE) 2003-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050261498-A1 Preparation of 4-amino-1-naphthol ethers NAP1L4, NAAA, NPEPPS DRD3 1514/4885
US-20030083525-A1 Preparation of 4-amino-1-naphthol ethers NAP1L4, NAAA, NPEPPS DRD3 1514/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.