Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.56 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3975213 | 0.99 | DPP4 (0.56) | DPP4CHRM1KCNH2CHRM2CHRM3 | |
| SCHEMBL4636235 | 0.90 | DPP4 (0.61) | DPP4CHRM1FAP | |
| Hydrochloric Acid SCHEMBL3967438 | 0.90 | DPP4 (0.60) | DPP4FAP | |
| SCHEMBL4634966 | 0.86 | DPP4 (0.59) | DPP4CHRM1FAP | |
| Hydrochloric Acid SCHEMBL3971423 | 0.85 | DPP4 (0.58) | DPP4FAP | |
| SCHEMBL4635303 | 0.85 | DPP4 (0.67) | DPP4KCNH2FAP | |
| Hydrochloric Acid SCHEMBL3969423 | 0.84 | DPP4 (0.66) | DPP4KCNH2FAP | |
| SCHEMBL6846120 | 0.84 | DPP4 (0.41) | DPP4CHRM1KCNH2CHRM2CHRM3 | |
| SCHEMBL3971099 | 0.82 | DPP4 (0.52) | DPP4CHRM1KCNH2CHRM2CHRM3 | |
| SCHEMBL3973862 | 0.82 | DPP4 (0.57) | DPP4CHRM1KCNH2CHRM2CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532150-B1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-11 | — | — | EP | disclosed |