Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | ACP1 | P24666 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4635037 | 1.00 | FFAR1 (0.49) | FFAR1ALOX5PTPN1ACP1CYP1A2 | |
| SCHEMBL4140267 | 0.90 | ALOX5 (0.47) | ALOX5PTPN1ACP1MEN1PIM1 | |
| SCHEMBL4140263 | 0.90 | ALOX5 (0.47) | ALOX5PTPN1ACP1MEN1PIM1 | |
| SCHEMBL4133440 | 0.89 | ALOX5 (0.54) | FFAR1ALOX5CYP1A2MEN1RAB9A | |
| SCHEMBL4133434 | 0.89 | ALOX5 (0.54) | FFAR1ALOX5CYP1A2MEN1RAB9A | |
| SCHEMBL4128880 | 0.83 | HDAC4 (0.44) | ALOX5CYP1A2MEN1RAB9AKMT2A | |
| SCHEMBL4128877 | 0.83 | HDAC4 (0.44) | ALOX5CYP1A2MEN1RAB9AKMT2A | |
| Propionic Acid SCHEMBL4295430 | 0.83 | ALOX5 (0.45) | ALOX5PTPN1ACP1MEN1PIM1 | |
| SCHEMBL4127367 | 0.82 | ALOX5 (0.51) | ALOX5PTPN1ACP1MEN1PIM1 | |
| SCHEMBL4127370 | 0.82 | ALOX5 (0.51) | ALOX5PTPN1ACP1MEN1PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101268060-A | Thiazolinone and oxazolinone compounds and application thereof as PTP1B inhibitor | TORRENT PHARMACEUTICALS LTD (IN) | 2008-09-17 | — | — | CN | claimed |
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |
| CN-101268060-A | Thiazolinone and oxazolinone compounds and application thereof as PTP1B inhibitor | TORRENT PHARMACEUTICALS LTD (IN) | 2008-09-17 | — | — | CN | disclosed |
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | disclosed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | disclosed |