Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.69 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.69 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.69 |
| ▸ | NAAA | Q02083 | 1/20 | 0.53 |
| ▸ | PRCP | P42785 | 2/20 | 0.51 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.49 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.49 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22178782 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL22179122 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL22178792 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL22179371 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL22179098 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL22179378 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL22178791 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL22178856 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| SCHEMBL11841856 | 0.94 | GNAI3 (0.80) | GNAI3GNAO1GNAI1NAAAPRCP | |
| Hydrochloric Acid SCHEMBL22160553 | 0.92 | GNAI3 (0.83) | GNAI3GNAO1GNAI1NAAAPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638933-B1 | N-PYRROLIDIN-3-YL-AMIDE DERIVATIVES AS SEROTONIN AND NORADRENALINE RE-UPTAKE INHIBITORS | PFIZER LTD (GB) | 2008-06-11 | — | — | EP | claimed |