Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD3 | P35462 | 4/20 | 0.38 |
| ▸ | SCN4A | P35499 | 2/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | MC1R | Q01726 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.37 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL463520 | 1.00 | KMT2A (0.44) | KMT2AL3MBTL1POLBPDE4BKDM1A | |
| SCHEMBL147896 | 0.93 | L3MBTL1 (0.46) | KMT2AL3MBTL1PDE4BKDM1AMAOB | |
| SCHEMBL147897 | 0.93 | L3MBTL1 (0.46) | KMT2AL3MBTL1PDE4BKDM1AMAOB | |
| SCHEMBL147898 | 0.93 | L3MBTL1 (0.46) | KMT2AL3MBTL1PDE4BKDM1AMAOB | |
| SCHEMBL459499 | 0.89 | KMT2A (0.44) | KMT2AL3MBTL1PDE4BKDM1AMAOB | |
| SCHEMBL459501 | 0.89 | KMT2A (0.44) | KMT2AL3MBTL1PDE4BKDM1AMAOB | |
| SCHEMBL143625 | 0.88 | MC1R (0.49) | KMT2AL3MBTL1DRD2DRD3MC1R | |
| SCHEMBL147672 | 0.88 | KMT2A (0.48) | KMT2AL3MBTL1DRD2DRD3DPP4 | |
| SCHEMBL143626 | 0.88 | MC1R (0.49) | KMT2AL3MBTL1DRD2DRD3MC1R | |
| SCHEMBL147670 | 0.88 | KMT2A (0.48) | KMT2AL3MBTL1DRD2DRD3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026587-A1 | 1,4 DISUBSTITUTED PYRROLIDINE - 3 - YL -AMINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2013-02-28 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |