Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 12/20 | 0.42 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | DUSP22 | Q9NRW4 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
| ▸ | MAX | P61244 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132445 | 0.91 | FFAR1 (0.47) | ALOX5FFAR1DUSP3DUSP22NR1H4 | |
| SCHEMBL4132443 | 0.91 | FFAR1 (0.47) | ALOX5FFAR1DUSP3DUSP22NR1H4 | |
| SCHEMBL4122528 | 0.90 | ALOX5 (0.46) | ALOX5PTPN22FFAR1DUSP3DUSP22 | |
| SCHEMBL4122531 | 0.90 | ALOX5 (0.46) | ALOX5PTPN22FFAR1DUSP3DUSP22 | |
| SCHEMBL4634747 | 0.89 | ALOX5 (0.52) | ALOX5PTPN22GSK3BKMT2ANR1H4 | |
| SCHEMBL4634749 | 0.89 | ALOX5 (0.52) | ALOX5PTPN22GSK3BKMT2ANR1H4 | |
| SCHEMBL4127925 | 0.88 | ALOX5 (0.53) | ALOX5MYCMAXGSK3BNR1H4 | |
| SCHEMBL4127928 | 0.88 | ALOX5 (0.53) | ALOX5MYCMAXGSK3BNR1H4 | |
| SCHEMBL4133988 | 0.87 | PDE4B (0.44) | ALOX5PTPN22FFAR1DUSP3DUSP22 | |
| SCHEMBL4131357 | 0.87 | ALOX5 (0.40) | ALOX5PTPN22FFAR1DUSP3DUSP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1934192-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | Torrent Pharmaceuticals Ltd (IN) | 2008-06-25 | — | — | EP | claimed |
| WO-2007032028-A1 | THIAZOLINONES AND OXAZOLINONES AND THEIR USE AS PTP1B INHIBITORS | TORRENT PHARMACEUTICALS LTD. (IN) | 2007-03-22 | — | — | WO | claimed |