Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3970583 | 0.99 | DPP4 (0.56) | DPP4TSHRNPSR1MEN1KMT2A | |
| SCHEMBL6843123 | 0.86 | TSHR (0.44) | DPP4TSHRNPSR1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL3971190 | 0.84 | DPP4 (0.48) | DPP4TSHRNPSR1MEN1KMT2A | |
| SCHEMBL4636235 | 0.83 | DPP4 (0.61) | DPP4TSHRFAPALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL3967438 | 0.82 | DPP4 (0.60) | DPP4TSHRFAPALDH1A1LMNA | |
| SCHEMBL3971432 | 0.81 | DPP4 (0.73) | DPP4TSHRNPSR1FAPALDH1A1 | |
| SCHEMBL4635303 | 0.81 | DPP4 (0.67) | DPP4TSHRFAPALDH1A1LMNA | |
| SCHEMBL3964227 | 0.81 | DPP4 (0.72) | DPP4TSHRNPSR1FAPALDH1A1 | |
| Hydrochloric Acid SCHEMBL3969423 | 0.80 | DPP4 (0.66) | DPP4TSHRFAPALDH1A1LMNA | |
| SCHEMBL4668818 | 0.80 | DPP4 (0.66) | DPP4TSHRNPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532150-B1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-11 | — | — | EP | disclosed |
| EP-1532150-A1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-05-25 | — | — | EP | disclosed |
| WO-2004018469-A1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-03-04 | — | — | WO | disclosed |