Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 5/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2689223 | 0.83 | SLC6A4 (0.71) | SLC6A2SLC6A4SLC6A3MAOBCYP1A2 | |
| SCHEMBL19321713 | 0.74 | CYP1A2 (0.45) | SLC6A2SLC6A4SLC6A3MAOBCYP1A2 | |
| SCHEMBL8804326 | 0.74 | CYP1A2 (0.45) | SLC6A2SLC6A4SLC6A3MAOBCYP1A2 | |
| SCHEMBL18499946 | 0.72 | ALOX5 (0.49) | SLC6A2SLC6A4SLC6A3MAOBCYP1A2 | |
| SCHEMBL15448408 | 0.67 | SLC6A2 (0.45) | SLC6A2SLC6A4SLC6A3CYP2A6 | |
| SCHEMBL2690240 | 0.67 | SLC6A4 (0.66) | SLC6A2SLC6A4SLC6A3MAOBTAAR1 | |
| SCHEMBL2689350 | 0.67 | SLC6A4 (0.66) | SLC6A2SLC6A4SLC6A3KCNH2 | |
| SCHEMBL2692483 | 0.67 | SLC6A4 (0.81) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2690027 | 0.67 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL2690100 | 0.67 | SLC6A2 (0.71) | SLC6A2SLC6A4SLC6A3MAOBTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771435-A4 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RES INST (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1771435-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | Human Biomolecular Research Institute (US) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006025920-A2 | MODULATORS OF CENTRAL NERVOUS SYSTEM NEUROTRANSMITTERS | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2006-03-09 | — | — | WO | disclosed |