Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 7/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | MAP4K1 | Q92918 | 5/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.33 |
| ▸ | TUBB | P07437 | 3/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2502825 | 0.95 | CTSA (0.40) | CTSASCN9ASCN10AGRIN1GRIN2B | |
| SCHEMBL2501087 | 0.92 | CTSA (0.36) | CTSASCN9ASCN10AGRIN1GRIN2B | |
| SCHEMBL2503551 | 0.90 | CTSA (0.35) | CTSASCN9ASCN10AMAP4K1TUBB4A | |
| SCHEMBL2503012 | 0.83 | CTSA (0.42) | CTSASCN9ASCN10AGRIN1GRIN2B | |
| SCHEMBL2497603 | 0.82 | SCN9A (0.34) | SCN9ASCN10A | |
| SCHEMBL2503116 | 0.82 | CTSA (0.40) | CTSASCN9ASCN10ATUBB4ATUBB | |
| SCHEMBL2497854 | 0.82 | GRM5 (0.43) | CTSASCN9ATUBB4ATUBBTUBA3C | |
| SCHEMBL2493706 | 0.82 | CTSA (0.41) | CTSASCN9ASCN10AGRIN1GRIN2B | |
| SCHEMBL2493853 | 0.81 | CTSA (0.39) | CTSASCN9ASCN10ATUBB4ATUBB | |
| SCHEMBL2495448 | 0.81 | TUBB4A (0.40) | CTSATUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937649-A1 | IMIDAZOLE DERIVATIVES FOR THE TREATMENT OF ANXIETY AND RELATED DISEASES | NEUROSEARCH A/S (DK) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007042546-A1 | IMIDAZOLE DERIVATIVES FOR THE TREATMENT OF ANXIETY AND RELATED DISEASES | NEUROSEARCH A/S (DK) | 2007-04-19 | — | — | WO | disclosed |