Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 10/20 | 0.43 |
| ▸ | TUBB | P07437 | 10/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 10/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 10/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 10/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 10/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 10/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 10/20 | 0.43 |
| ▸ | TUBB8 | Q3ZCM7 | 10/20 | 0.43 |
| ▸ | TUBA3E | Q6PEY2 | 10/20 | 0.43 |
| ▸ | TUBA1A | Q71U36 | 10/20 | 0.43 |
| ▸ | TUBA1C | Q9BQE3 | 10/20 | 0.43 |
| ▸ | TUBB6 | Q9BUF5 | 10/20 | 0.43 |
| ▸ | TUBB2B | Q9BVA1 | 10/20 | 0.43 |
| ▸ | TUBB1 | Q9H4B7 | 10/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4636183 | 0.96 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2499569 | 0.95 | TUBB4A (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2495983 | 0.94 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2500270 | 0.89 | TUBB4A (0.46) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2501099 | 0.88 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2499722 | 0.87 | TUBB4A (0.48) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2501518 | 0.87 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2496214 | 0.86 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4637194 | 0.85 | TUBB4A (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL2498106 | 0.84 | TUBB4A (0.45) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937649-A1 | IMIDAZOLE DERIVATIVES FOR THE TREATMENT OF ANXIETY AND RELATED DISEASES | NEUROSEARCH A/S (DK) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007042546-A1 | IMIDAZOLE DERIVATIVES FOR THE TREATMENT OF ANXIETY AND RELATED DISEASES | NEUROSEARCH A/S (DK) | 2007-04-19 | — | — | WO | disclosed |