Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | FAP | Q12884 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4082595 | 0.91 | DPP4 (0.53) | DPP4CYP3A4FAP | |
| SCHEMBL3967148 | 0.79 | DPP4 (0.54) | DPP4CYP3A4FAP | |
| SCHEMBL3969500 | 0.79 | DPP4 (0.54) | DPP4CYP3A4FAP | |
| SCHEMBL3971411 | 0.78 | DPP4 (0.56) | DPP4FAP | |
| SCHEMBL3971487 | 0.78 | DPP4 (0.58) | DPP4FAP | |
| SCHEMBL3976287 | 0.77 | DPP4 (0.54) | DPP4CYP3A4FAP | |
| SCHEMBL3969378 | 0.77 | DPP4 (0.51) | DPP4FAP | |
| SCHEMBL3967774 | 0.77 | DPP4 (0.53) | DPP4CYP3A4FAP | |
| SCHEMBL3968988 | 0.77 | DPP4 (0.62) | DPP4 | |
| SCHEMBL3970033 | 0.77 | DPP4 (0.58) | DPP4FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532150-B1 | NOVEL PURINE DERIVATIVES, PRODUCTION AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2008-06-11 | — | — | EP | disclosed |