Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541195 | 0.83 | ADORA2A (0.52) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL2542741 | 0.82 | ADORA2B (0.50) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL2570140 | 0.82 | ADORA2B (0.47) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL2538710 | 0.81 | ADORA2B (0.49) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL2545132 | 0.80 | ADORA2B (0.47) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL2540260 | 0.79 | ADORA1 (0.55) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL2541470 | 0.79 | ADORA1 (0.56) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL18990264 | 0.79 | ADORA2B (0.58) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL2542730 | 0.78 | ADORA2B (0.46) | ADORA2BGLABLMADORA2AADORA1 | |
| SCHEMBL12233685 | 0.78 | ADORA2B (0.46) | ADORA2BGLABLMADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939197-A1 | 8-ethinylxanthine derivatives as selective A2A receptor antagonists | SCHWARZ PHARMA AG (DE) | 2008-07-02 | — | — | EP | disclosed |