Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL163750 | 0.80 | ESR1 (0.43) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL8755636 | 0.78 | ESR1 (0.42) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL27978287 | 0.78 | ESR1 (0.42) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL4455459 | 0.72 | ACP3 (0.39) | ESR1ACP3ALDH1A1GAAMEN1 | |
| SCHEMBL10902580 | 0.70 | ESR1 (0.34) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL23361811 | 0.69 | ESR1 (0.54) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL27510474 | 0.69 | CYP3A4 (0.39) | ESR1TSHRCYP3A4SLC6A2MAPT | |
| SCHEMBL331134 | 0.69 | MIF (0.39) | TSHRALDH1A1CYP3A4SLC6A2LMNA | |
| SCHEMBL7331227 | 0.68 | ESR1 (0.52) | ESR1ACP3TSHRACHEALDH1A1 | |
| SCHEMBL3981386 | 0.68 | ESR1 (0.31) | ESR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893590-A1 | BENZOOXAZOLE-2-ON DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | Sanofi-Aventis (FR) | 2008-03-05 | — | — | EP | disclosed |
| EP-1874741-A1 | AZOLE DERIVATIVES IN THE FORM OF LIPASE AND PHOSPHOLIPASE INHIBITORS | sanofi-aventis (FR) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006131233-A1 | BENZOOXAZOLE-2-ON DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI-AVENTIS (FR) | 2006-12-14 | — | — | WO | disclosed |
| WO-2006111321-A1 | AZOLE DERIVATIVES IN THE FORM OF LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI-AVENTIS (DE) | 2006-10-26 | — | — | WO | disclosed |