SCHEMBL163750

SCHEMBL163750

Cc1ccccc1C(N=C=O)N=C=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.43
ACP3 P15309 1/20 0.38
TSHR P16473 3/20 0.36
ACHE P22303 1/20 0.36
ALDH1A1 P00352 3/20 0.33
CYP3A4 P08684 2/20 0.33
SLC6A2 P23975 2/20 0.33
SLC6A4 P31645 2/20 0.33
SLC6A3 Q01959 2/20 0.33
GAA P10253 1/20 0.33
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
PRSS1 P07477 1/20 0.31
CTSG P08311 1/20 0.31
CTRB1 P17538 1/20 0.31
CMA1 P23946 1/20 0.31
CYP2D6 P10635 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10902580 0.85 ESR1 (0.34) ESR1ACP3TSHRACHEALDH1A1
SCHEMBL3981386 0.84 ESR1 (0.31) ESR1CYP3A4
SCHEMBL27510474 0.84 CYP3A4 (0.39) ESR1TSHRCYP3A4SLC6A2MAPT
SCHEMBL8755636 0.82 ESR1 (0.42) ESR1ACP3TSHRACHEALDH1A1
SCHEMBL27978287 0.82 ESR1 (0.42) ESR1ACP3TSHRACHEALDH1A1
SCHEMBL4637046 0.80 ESR1 (0.41) ESR1ACP3TSHRACHEALDH1A1
SCHEMBL16165919 0.78 CDC25B (0.36) ALDH1A1CYP3A4MEN1LMNAMAPT
SCHEMBL58375 0.76 TP53 (0.34) ALDH1A1CYP3A4SLC6A2MEN1LMNA
SCHEMBL4455459 0.74 ACP3 (0.39) ESR1ACP3ALDH1A1GAAMEN1
SCHEMBL4996374 0.74 TRPA1 (0.31) CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 362 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119907820-A Isocyanate composition 韩华思路信(株) 2025-04-29 CN claimed
CN-118317988-A Isocyanate composition and process for producing the same 韩华思路信(株) 2024-07-09 CN claimed
CN-117659346-A Novel high-toughness recyclable room-temperature self-repairing polyurethane and preparation method thereof 电子科技大学长三角研究院(湖州) 2024-03-08 CN claimed
CN-115181535-B Ultraviolet light-moisture dual-curing polyurethane hot melt adhesive and preparation method thereof 苏州合邦鑫材科技有限公司 2024-01-12 CN claimed
CN-117304863-A LED-UV (light-emitting diode-ultraviolet) curing type strippable protective adhesive as well as preparation method and application thereof 天津科技大学 2023-12-29 CN claimed
CN-115181535-A Ultraviolet light-moisture dual-curing polyurethane hot melt adhesive and preparation method thereof 苏州合邦鑫材科技有限公司 2022-10-14 CN claimed
EP-2949691-B1 METHOD FOR MANUFACTURING PLASTIC FILM LG CHEMICAL LTD (KR) 2021-12-15 EP claimed
EP-2949709-B1 PLASTIC FILM LG CHEMICAL LTD (KR) 2020-04-29 EP claimed
EP-2949713-B1 COATING COMPOSITION LG CHEMICAL LTD (KR) 2017-10-25 EP claimed
US-7196154-B2 Method of producing polymer resins LIGHT BLACK INC. (JP) 2007-03-27 US claimed
US-20020166630-A1 Method of producing polymer resins LIGHT BLACK U.S.A., INC. 2002-11-14 US claimed
CN-1207501-A Lenses obtained from high-speed polymerizable resin composition MITSUI CHEMICALS INC (JP) 1999-02-10 CN claimed
CN-122055676-A Resin composition, cured product, display device, or semiconductor device 东丽株式会社 2026-05-15 CN disclosed
US-20260009940-A1 OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2026-01-08 US disclosed
EP-3916471-B1 PLASTIC LENS AND EYE GLASSES TOKAI OPTICAL CO LTD (JP) 2025-11-12 EP disclosed
US-12461296-B2 Optical laminate and image display device FUJIFILM CORPORATION (JP) 2025-11-04 US disclosed
EP-0278305-A1 Transparent coating system for providing long term exterior durability to wood PPG INDUSTRIES, INC. (US) 1988-08-17 EP disclosed
EP-0080031-B1 POLYURETHANES USEFUL AS ENGINEERING PLASTICS THE DOW CHEMICAL COMPANY (US) 1988-01-07 EP disclosed
EP-0234308-A2 Coating composition containing an ungelled reaction product as a curative PPG INDUSTRIES, INC. (US) 1987-09-02 EP disclosed
US-4678835-A AMINE AND SILICON-CONTAINING PPG INDUSTRIES, INC. (US) 1987-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020166630-A1 Method of producing polymer resins PARG, PNMT, ALKBH5 ESR1 3938/4885ACP3 857/4885TSHR 3617/4885
US-20260009940-A1 OPTICAL LAMINATE AND IMAGE DISPLAY DEVICE CDH1, ITGA1, ITGAL ESR1 160/4885ACP3 3060/4885TSHR 4570/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.