Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 7/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 6/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.46 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13561938 | 1.00 | ERAP2 (0.47) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL13496274 | 0.90 | ERAP2 (0.54) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL2734207 | 0.87 | ERAP2 (0.52) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL13561939 | 0.84 | CA12 (0.40) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL411635 | 0.84 | KMT2A (0.58) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL13079511 | 0.84 | GNAI3 (0.54) | ERAP2LNPEPERAP1DPP7GNAI3 | |
| SCHEMBL24198900 | 0.83 | FOLH1 (0.51) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL21454270 | 0.83 | FOLH1 (0.51) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL31735185 | 0.83 | FOLH1 (0.51) | ERAP2LNPEPERAP1DPP8DPP9 | |
| SCHEMBL11982689 | 0.83 | DPP4 (0.50) | ERAP2DPP8DPP9CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871252-B2 | pH-responsive liposome | NANOTHETA CO, LTD. (JP) | 2014-10-28 | — | — | US | disclosed |
| US-8338643-B2 | Reagent for introduction of protein or gene | WASEDA UNIVERSITY (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | BIONANOSHEETER CO., LTD. (JP) | 2012-03-15 | — | — | US | disclosed |
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | WASEDA UNIVERSITY (JP) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120064148-A1 | PH-RESPONSIVE LIPOSOME | LIPA, SMPD3, SMPD1 | ERAP2 1951/4885LNPEP 164/4885ERAP1 2219/4885 |
| US-20100291672-A1 | REAGENT FOR INTRODUCTION OF PROTEIN OR GENE | C1S, SGMS1, CERT1 | ERAP2 2020/4885LNPEP 204/4885ERAP1 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.