Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.34 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27746551 | 0.88 | PTGDR2 (0.42) | BRD4POLB | |
| SCHEMBL883916 | 0.87 | MAPT (0.44) | POLBSCN9AEPAS1SLC22A12LMNA | |
| SCHEMBL883838 | 0.84 | NR3C1 (0.42) | EPAS1 | |
| SCHEMBL586221 | 0.75 | SCN9A (0.34) | BRD4SCN9AEPAS1SLC22A12 | |
| SCHEMBL883887 | 0.75 | FFAR1 (0.45) | EPAS1FFAR1 | |
| SCHEMBL12776396 | 0.74 | EPAS1 (0.41) | EPAS1FFAR1 | |
| SCHEMBL883834 | 0.74 | PTGDR2 (0.45) | EPAS1FFAR1 | |
| SCHEMBL586177 | 0.73 | EGFR (0.40) | SCN9AEPAS1FFAR1 | |
| SCHEMBL883847 | 0.73 | PTGDR2 (0.48) | BRD4 | |
| SCHEMBL883915 | 0.73 | NR3C1 (0.42) | EPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937632-A1 | NOVEL COMPOUNDS | Astra Zeneca AB (SE) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007039736-A1 | NOVEL COMPOUNDS | ASTRAZENECA AB (SE) | 2007-04-12 | — | — | WO | disclosed |