SCHEMBL4637577

SCHEMBL4637577

CC(C)CC1CN(C(=O)O)CCc2cc(N3CC[C@H](NS(=O)(=O)c4ccc5c(Cl)c[nH]c5c4)C3=O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4638229 0.85 F10 (0.66) F10
SCHEMBL5428069 0.80 F10 (1.00) F10
SCHEMBL4638226 0.79 F10 (0.68) F10
SCHEMBL5431197 0.79 F10 (1.00) F10
SCHEMBL4925302 0.78 F10 (0.68) F10
SCHEMBL4170624 0.77 F10 (0.66) F10
SCHEMBL5428126 0.76 F10 (0.80) F10
SCHEMBL4932723 0.76 F10 (0.90) F10
Hydrochloric Acid SCHEMBL4927324 0.75 F10 (0.89) F10
SCHEMBL4172349 0.74 F10 (1.00) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951712-A2 CHEMICAL COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-08-06 EP disclosed
WO-2007059952-A2 1-BENZAZEPINE-3-SULFONYLAMINO-2-PYRRLORIDONES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2007-05-31 WO disclosed