SCHEMBL4638229

SCHEMBL4638229

CC(C)CC1c2ccc(N3CC[C@H](NS(=O)(=O)c4ccc5c(Cl)c[nH]c5c4)C3=O)cc2CCCN1C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4638226 0.87 F10 (0.68) F10
SCHEMBL4637577 0.85 F10 (0.66) F10
SCHEMBL5279883 0.81 F10 (0.65) F10
SCHEMBL5288806 0.81 F10 (0.65) F10
SCHEMBL5275478 0.81 F10 (0.47) F10
SCHEMBL5428069 0.80 F10 (1.00) F10
SCHEMBL5431197 0.79 F10 (1.00) F10
SCHEMBL4639287 0.78 F10 (1.00) F10
SCHEMBL4176267 0.78 F10 (1.00) F10
SCHEMBL4932723 0.77 F10 (0.90) F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1951712-A2 CHEMICAL COMPOUNDS GLAXO GROUP LIMITED (GB) 2008-08-06 EP disclosed
WO-2007059952-A2 1-BENZAZEPINE-3-SULFONYLAMINO-2-PYRRLORIDONES AS FACTOR XA INHIBITORS GLAXO GROUP LIMITED (GB) 2007-05-31 WO disclosed