Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 11/20 | 0.55 |
| ▸ | PPARG | P37231 | 10/20 | 0.55 |
| ▸ | PPARA | Q07869 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637576 | 0.89 | PPARD (0.55) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL334519 | 0.86 | PPARD (0.62) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL334683 | 0.85 | PPARG (0.53) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL4638656 | 0.83 | PPARD (0.49) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL27727139 | 0.81 | NPC1 (0.48) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL335857 | 0.81 | NPC1 (0.55) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL27878983 | 0.81 | PPARG (0.64) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL10221033 | 0.76 | PPARD (0.59) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL14143957 | 0.75 | PPARG (0.51) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL10221037 | 0.75 | PPARD (0.60) | PPARDPPARGPPARANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |