Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 10/20 | 0.49 |
| ▸ | PPARG | P37231 | 9/20 | 0.49 |
| ▸ | PPARA | Q07869 | 6/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4637576 | 0.88 | PPARD (0.55) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL334260 | 0.87 | PPARD (0.55) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL334141 | 0.87 | PPARG (0.48) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL10271876 | 0.86 | NPC1 (0.45) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL10221055 | 0.83 | PPARD (0.67) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL4637598 | 0.83 | PPARD (0.55) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL10221031 | 0.82 | PPARD (0.58) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL10221018 | 0.79 | PPARD (0.58) | PPARDPPARGPPARANPC1RAB9A | |
| SCHEMBL334515 | 0.78 | PPARD (0.69) | PPARDPPARGPPARACYP2C9 | |
| SCHEMBL334392 | 0.77 | PPARD (0.59) | PPARDPPARGPPARATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1939189-A1 | DERIVATIVE HAVING PPAR AGONISTIC ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |