Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1184606 | 0.84 | NR1H4 (0.47) | NR1H4SLC10A2 | |
| SCHEMBL4598864 | 0.74 | NR1H4 (0.47) | NR1H4 | |
| SCHEMBL5690082 | 0.74 | NR1H4 (0.48) | NR1H4 | |
| SCHEMBL3875478 | 0.72 | MTTP (0.32) | — | |
| SCHEMBL24437501 | 0.72 | NR1H4 (0.51) | NR1H4SLC10A2 | |
| SCHEMBL4642249 | 0.71 | NR1H4 (0.50) | NR1H4SLC10A2 | |
| SCHEMBL26235945 | 0.70 | NR1H4 (0.79) | NR1H4SLC10A2 | |
| SCHEMBL5274004 | 0.70 | NR1H4 (0.47) | NR1H4 | |
| SCHEMBL919321 | 0.70 | NR1H4 (0.79) | NR1H4SLC10A2 | |
| SCHEMBL4660631 | 0.70 | NR1H4 (0.48) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879860-A2 | 1,4-DIPHENYL-3-HYDROXYALKYL-2-AZETIDINONE DERIVATIVES FOR TREATING HYPERCHOLESTROLEMIA | Microbia Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006122186-A2 | 1,4-DIPHENYL-3-HYDROXYALKYL-2-AZETIDINONE DERIVATIVES FOR TREATING HYPERCHOLESTROLEMIA | MICROBIA, INC. (US) | 2006-11-16 | — | — | WO | disclosed |