Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTTP | P55157 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL931590 | 0.84 | SLC10A2 (0.36) | MTTP | |
| SCHEMBL3611683 | 0.80 | SLC10A2 (0.34) | MTTP | |
| SCHEMBL5762558 | 0.79 | SLC10A2 (0.53) | — | |
| Ammonia Solution, Strong SCHEMBL1183723 | 0.78 | SLC10A2 (0.52) | — | |
| SCHEMBL4790922 | 0.76 | SLC10A2 (0.44) | — | |
| Ammonia Solution, Strong SCHEMBL3611677 | 0.76 | SLC10A2 (0.49) | — | |
| SCHEMBL4637650 | 0.72 | NR1H4 (0.41) | — | |
| Ammonia Solution, Strong SCHEMBL5497725 | 0.70 | SLC10A2 (0.52) | — | |
| Ammonia Solution, Strong SCHEMBL3875475 | 0.68 | — | — | |
| SCHEMBL920147 | 0.64 | SLC10A2 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013165-A1 | DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSOR TION INHIBITOR ACTIVIT. | Astra Zeneca AB (SE) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007126358-A1 | DIPHENYLAZETIDINONE DERIVATES POSSESSING CHOLESTEROL ABSOR TION INHIBITOR ACTIVIT. | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | WO | disclosed |
| EP-1699758-A1 | DIPHENYLAZETIDINONE DERIVATES PROCESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005061451-A1 | DIPHENYLAZETIDINONE DERIVATES PROCESSING CHOLESTEROL ABSORPTION INHIBITORY ACTIVITY | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | disclosed |