Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2075913 | 1.00 | TMEM97 (0.51) | TMEM97SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL12201661 | 0.90 | TMEM97 (0.49) | TMEM97SIGMAR1TAAR1MEN1KMT2A | |
| SCHEMBL28773466 | 0.84 | TMEM97 (0.38) | TMEM97SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11105943 | 0.83 | TMEM97 (0.56) | TMEM97SIGMAR1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8479576 | 0.82 | SLC6A2 (0.52) | TMEM97SIGMAR1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL7834371 | 0.82 | SLC6A2 (0.52) | TMEM97SIGMAR1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL7834832 | 0.82 | SLC6A2 (0.52) | TMEM97SIGMAR1SLC6A2SLC6A4CYP3A4 | |
| SCHEMBL4191243 | 0.80 | TMEM97 (0.46) | TMEM97SIGMAR1TAAR1MEN1KMT2A | |
| SCHEMBL3232098 | 0.80 | TMEM97 (0.46) | TMEM97SIGMAR1CYP3A4MEN1KMT2A | |
| SCHEMBL12163921 | 0.80 | TMEM97 (0.38) | TMEM97SIGMAR1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891005-A2 | PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2 ALPHA DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006112742-A2 | PROCESS FOR PREPARATION OF 13,14-DIHYDRO-PGF2α DERIVATIVES | INSTYTUT FARMACEUTYCZNY (PL) | 2006-10-26 | — | — | WO | disclosed |
| US-5247085-A | Phosphonate containing purine compounds | BEECHAM GROUP P.L.C. (GB) | 1993-09-21 | — | — | US | disclosed |
| EP-0405748-A1 | Phosphonoderivative of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1991-01-02 | — | — | EP | disclosed |