SCHEMBL463777

SCHEMBL463777

C=C/C=C(/N)C=C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18831062 0.85 ALDH1A1 (0.44)
SCHEMBL19706348 0.84 ALDH1A1 (0.33)
SCHEMBL14309736 0.78
SCHEMBL14395016 0.78
SCHEMBL20841248 0.74
SCHEMBL18935738 0.73
SCHEMBL18473368 0.73 ALDH1A1 (0.35)
SCHEMBL19074900 0.73
SCHEMBL6395521 0.73
SCHEMBL6395507 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS FIREFLY BIO, INC. 2024-02-29 US disclosed
US-11702509-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-07-18 US disclosed
US-11518734-B2 Monomer and polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO., LTD. (KR) 2022-12-06 US disclosed
US-20200407548-A1 EPOXY RESIN COMPOSITION, PREPREG, FIBER REINFORCED COMPOSITE MATERIAL, AND PRODUCTION METHODS THEREFOR TEIJIN LIMITED (JP) 2020-12-31 US disclosed
US-20200377659-A1 MONOMER, POLYMER, COMPENSATION FILM, OPTICAL FILM, AND DISPLAY DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2020-12-03 US disclosed
US-10808080-B2 Monomer, polymer, compensation film, optical film, and display device SAMSUNG ELECTRONICS CO, LTD. (KR) 2020-10-20 US disclosed
US-10538666-B2 Compound, polymer, film, and optical device SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-01-21 US disclosed
US-20190256659-A1 POLYMER, FILM INCLUDING THE POLYMER, AND DISPLAY DEVICE INCLUDING THE FILM SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-22 US disclosed
US-20190233643-A1 COMPOUND, POLYMER, FILM, AND OPTICAL DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2019-08-01 US disclosed
WO-2019062949-A1 COMPOUND HAVING ERK KINASE INHIBITORY ACTIVITY AND USE THEREOF 上海海和药物研究开发有限公司 2019-04-04 WO disclosed
US-8344138-B2 Triazinedione derivatives as GABAB receptor modulators ADDEX PHARMA S.A. (CH) 2013-01-01 US disclosed
US-20120301875-A1 AMPLICON MELTING ANALYSIS WITH SATURATION DYES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2012-11-29 US disclosed
US-20120065395-A1 2,4 (4,6) PYRIMIDINE DERIVATIVES FREYNE EDDY JEAN EDGARD (BE) 2012-03-15 US disclosed
US-8057918-B2 Organic light-emitting diodes and methods for assembly and enhanced charge injection NORTHWESTERN UNIVERSITY (US) 2011-11-15 US disclosed
US-7803551-B2 Amplifying the target nucleic acid with primers in the presence of a double-stranded DNA binding dye; monitoring fluorescence of the dye; melting curve is generated for the target nucleic acid by measuring fluorescence from the dsDNA binding dye as the mixture is heated. UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2010-09-28 US disclosed
EP-1445600-B1 Optical switch and safety apparatus using the same FUJIFILM CORP (JP) 2010-05-05 EP disclosed
US-20100041044-A1 Amplifying the target nucleic acid with primers in the presence of a double-stranded DNA binding dye; monitoring fluorescence of the dye; melting curve is generated for the target nucleic acid by measuring fluorescence from the dsDNA binding dye as the mixture is heated. BIOFIRE DIAGNOSTICS, INC. 2010-02-18 US disclosed
US-20100004246-A1 NOVEL TRIAZINEDIONE DERIVATIVES AS GABAB RECEPTOR MODULATORS ADDEX PHARMA SA (CH) 2010-01-07 US disclosed
EP-1562911-B1 COMPOSITIONS USEFUL AS INHIBITORS OF JAK AND OTHER PROTEIN KINASES VERTEX PHARMA (US) 2010-01-06 EP disclosed
US-7582429-B2 Polymerase chain reaction analysis by mixing a dsDNA binding dye with a sample of target nucleic acid and primers configured for amplifying; melting the amplified target nucleic acid to generate a melting curve; plotting; repeating; comparison; melting curve difference for each target nucleic acid UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2009-09-01 US disclosed