⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3070359 | 0.65 | NOTUM (0.33) | — | |
| SCHEMBL171550 | 0.60 | — | — | |
| SCHEMBL60018 | 0.60 | — | — | |
| SCHEMBL74852 | 0.60 | — | — | |
| SCHEMBL2643021 | 0.60 | — | — | |
| SCHEMBL23808321 | 0.60 | — | — | |
| SCHEMBL74851 | 0.60 | — | — | |
| SCHEMBL9697518 | 0.60 | — | — | |
| SCHEMBL5561360 | 0.60 | — | — | |
| SCHEMBL7757478 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104039801-A | Tungsten oxo alkylidene complexes for Z selective olefin metathesis | MASSACHUSETTS INST TECHNOLOGY | 2014-09-10 | — | — | CN | claimed |
| CN-108976272-A | The disubstituted 19- norpregna hydride compounds of 3,3-, composition, and application thereof | 萨奇治疗股份有限公司 | 2018-12-11 | — | — | CN | disclosed |
| CN-104039801-B | TUNGSTEN OXO ALKYLIDENE COMPLEXES FOR Z SELECTIVE OLEFIN METATHESIS | 麻省理工学院 | 2017-05-10 | — | — | CN | disclosed |
| CN-102712633-A | Inhibitors of flaviviridae viruses | GILEAD SCIENCES INC (US) | 2012-10-03 | — | — | CN | disclosed |
| CN-102712632-A | Inhibitors of flaviviridae viruses | GILEAD SCIENCES INC (US) | 2012-10-03 | — | — | CN | disclosed |
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |
| US-7179804-B2 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 2007-02-20 | — | — | US | disclosed |
| US-20050239776-A1 | Tachykinin receptor antagonists | ELI LILLY AND COMPANY (US) | 2005-10-27 | — | — | US | disclosed |
| EP-1501808-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-02-02 | — | — | EP | disclosed |
| WO-2003091227-A1 | TACHYKININ RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-06 | — | — | WO | disclosed |