Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
| ▸ | GALR3 | O60755 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4638811 | 0.90 | IDH1 (0.40) | CYP19A1ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL4637813 | 0.88 | IDH1 (0.39) | CYP19A1ALDH1A1TSHRSMN1; SMN2CYP3A4 | |
| SCHEMBL4638053 | 0.81 | ALDH1A1 (0.44) | CYP19A1ALDH1A1TSHRMAPTPOLB | |
| SCHEMBL4638504 | 0.81 | CYP19A1 (0.36) | CYP19A1ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL4638905 | 0.79 | IDH1 (0.41) | CYP19A1ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL4637714 | 0.79 | IDH1 (0.54) | CYP19A1ALDH1A1TSHRP2RX7HIF1A | |
| SCHEMBL4639451 | 0.79 | CYP19A1 (0.48) | CYP19A1ALDH1A1TSHRSMN1; SMN2P2RX7 | |
| SCHEMBL4707915 | 0.79 | IDH1 (0.48) | CYP19A1ALDH1A1TSHRP2RX7 | |
| SCHEMBL4637949 | 0.78 | IDH1 (0.39) | CYP19A1ALDH1A1TSHRSMN1; SMN2MAPT | |
| SCHEMBL4707175 | 0.77 | MAPT (0.46) | ALDH1A1TSHRSMN1; SMN2MAPTP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501808-B1 | TACHYKININ RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2008-07-02 | — | — | EP | disclosed |