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Sulfamide

Sulfamide

SCHEMBL4638516

Clc1ccc(C2=C(c3ccccc3)CC3(CC3)C2)cc1Cl.NS(N)(=O)=O

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 20/20 0.75
▸ PTGS1 P23219 14/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL215552 0.86 PTGS2 (1.00) PTGS2PTGS1
Sulfamide SCHEMBL4639820 0.84 PTGS2 (0.78) PTGS2PTGS1
SCHEMBL8385166 0.80 PTGS2 (1.00) PTGS2PTGS1
SCHEMBL8388650 0.78 PTGS2 (0.71) PTGS2PTGS1
SCHEMBL8386271 0.77 PTGS2 (0.74) PTGS2PTGS1
SCHEMBL8388182 0.77 PTGS2 (0.70) PTGS2PTGS1
SCHEMBL8383821 0.77 PTGS2 (0.70) PTGS2PTGS1
SCHEMBL8388633 0.75 PTGS2 (0.80) PTGS2PTGS1
SCHEMBL8383971 0.75 PTGS2 (0.80) PTGS2PTGS1
SCHEMBL8384272 0.74 PTGS2 (0.81) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1479385-B1 Use of cyclooxygenase-2 inhibitors in the treatment and prevention of neoplasia SEARLE LLC (US) 2008-07-02 — — EP claimed