Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069987 | 0.98 | JAK3 (0.34) | JAK3GRM5HPGDALDH1A1HDAC1 | |
| SCHEMBL2491805 | 0.79 | SMN1; SMN2 (0.40) | JAK3GRM5HDAC1HDAC6BACE1 | |
| SCHEMBL29361842 | 0.79 | SMN1; SMN2 (0.40) | JAK3GRM5HDAC1HDAC6BACE1 | |
| SCHEMBL30112052 | 0.79 | HPGD (0.39) | JAK3GRM5HPGDALDH1A1HDAC1 | |
| SCHEMBL7422568 | 0.79 | HPGD (0.39) | JAK3GRM5HPGDALDH1A1HDAC1 | |
| SCHEMBL3460085 | 0.78 | SIRT3 (0.37) | JAK3GRM5ALDH1A1POLBKDM4E | |
| SCHEMBL30509867 | 0.78 | SIRT3 (0.37) | JAK3GRM5ALDH1A1POLBKDM4E | |
| SCHEMBL3168026 | 0.77 | JAK3 (0.33) | JAK3GRM5HPGDALDH1A1HDAC1 | |
| SCHEMBL9190262 | 0.76 | POLB (0.35) | JAK3GRM5POLB | |
| SCHEMBL11201451 | 0.74 | MAPKAPK2 (0.35) | JAK3GRM5HPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924268-A2 | SYNTHESIS OF 1ALPHA-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | Bioxell S.p.a. (IT) | 2008-05-28 | — | — | EP | claimed |
| WO-2007022433-A2 | SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | BIOXELL S.P.A. (IT) | 2007-02-22 | — | — | WO | claimed |