Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14404998 | 0.75 | CHRM2 (0.38) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL15978072 | 0.70 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL20995891 | 0.67 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7920287 | 0.67 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7926056 | 0.67 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL789252 | 0.67 | CHRM2 (0.53) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7926060 | 0.67 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL4178422 | 0.66 | CDC25A (0.42) | — | |
| SCHEMBL13853984 | 0.66 | CDC25A (0.50) | MEN1KMT2A | |
| SCHEMBL13392639 | 0.66 | CDC25A (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1924268-A2 | SYNTHESIS OF 1ALPHA-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | Bioxell S.p.a. (IT) | 2008-05-28 | — | — | EP | disclosed |
| WO-2007022433-A2 | SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | BIOXELL S.P.A. (IT) | 2007-02-22 | — | — | WO | disclosed |