Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15978072 | 0.76 | CHRM2 (0.40) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL29027145 | 0.76 | GRIN1 (0.46) | MEN1CYP2D6KMT2ACYP3A4GRIN1 | |
| SCHEMBL4639080 | 0.75 | CHRM2 (0.36) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL31267268 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP3A4GRIN1GRIN2B | |
| SCHEMBL10125299 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP3A4GRIN1GRIN2B | |
| SCHEMBL8831381 | 0.75 | CHRM2 (0.36) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL9009451 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP3A4GRIN1GRIN2B | |
| SCHEMBL9009430 | 0.75 | MEN1 (0.47) | MEN1KMT2ACYP3A4GRIN1GRIN2B | |
| SCHEMBL13768952 | 0.75 | CHRM2 (0.48) | CHRM2CHRM1CHRM4CHRM3MEN1 | |
| SCHEMBL7151331 | 0.73 | CHRM2 (0.33) | CHRM2CHRM1CHRM4CHRM3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110109-A1 | NOVEL METHOD | BIOXELL SPA (IT) | 2007-10-04 | — | — | WO | disclosed |
| WO-2007022433-A2 | SYNTHESIS OF 1α-FLUORO-25-HYDROXY-16-23E-DIENE-26,27-BISHOMO-20-EPI-CHOLECALCIFEROL | BIOXELL S.P.A. (IT) | 2007-02-22 | — | — | WO | disclosed |