⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310293 | 0.78 | — | — | |
| SCHEMBL269675 | 0.74 | — | — | |
| SCHEMBL2515025 | 0.74 | — | — | |
| SCHEMBL276851 | 0.67 | ALDH1A1 (0.42) | — | |
| SCHEMBL4736362 | 0.67 | — | — | |
| SCHEMBL6722126 | 0.65 | — | — | |
| SCHEMBL28784371 | 0.65 | — | — | |
| SCHEMBL270998 | 0.64 | — | — | |
| SCHEMBL5178972 | 0.63 | — | — | |
| SCHEMBL12852586 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1888532-A1 | HETEROAROYL-SUBSTITUTED SERINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2008-02-20 | — | — | EP | disclosed |
| EP-1791825-A1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006125687-A1 | HETEROAROYL-SUBSTITUTED SERINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006029828-A1 | BENZOYL-SUBSTITUTED SERINE AMIDES | BASF AKTIENGESELLSCHAFT (DE) | 2006-03-23 | — | — | WO | disclosed |
| EP-1135385-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-1080089-A1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2001-03-07 | — | — | EP | disclosed |
| WO-2000034270-A1 | THIOCHROMANOYLPYRAZOLONE DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | disclosed |
| WO-1999059991-A1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-25 | — | — | WO | disclosed |