Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 4/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 4/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4280795 | 0.94 | KDM4E (0.54) | FFAR1FFAR4KDM4EALDH1A1TSHR | |
| SCHEMBL4277665 | 0.89 | KDM4E (0.47) | FFAR1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4271756 | 0.88 | TSHR (0.48) | FFAR1FFAR4KDM4EALDH1A1TSHR | |
| SCHEMBL27918456 | 0.86 | FFAR1 (0.45) | FFAR1FFAR4KDM4EALDH1A1TSHR | |
| SCHEMBL4270615 | 0.86 | SMPD1 (0.48) | FFAR1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4271285 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1TSHRHSD17B10MAPT | |
| SCHEMBL4639705 | 0.84 | TSHR (0.45) | FFAR1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4270587 | 0.84 | ABCB1 (0.43) | FFAR1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4282880 | 0.83 | TSHR (0.42) | FFAR1KDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL4270619 | 0.82 | KDM4E (0.49) | FFAR1KDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1954684-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007058338-A2 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-05-24 | — | — | WO | disclosed |