SCHEMBL4639616

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL810623	0.81	MAOB (0.72)	MAOBAPPTP53CYP3A4MAPT
	SCHEMBL110283	0.80	CYP3A4 (0.54)	MAOBAPPTP53CYP3A4GAA
	SCHEMBL29375904	0.80	CYP3A4 (0.54)	MAOBAPPTP53CYP3A4GAA
	SCHEMBL9795738	0.80	MAOB (0.70)	MAOBAPPTP53CYP3A4RAB9A
	SCHEMBL4639608	0.79	MRGPRX4 (0.61)	MAOBMRGPRX4F2MAOA
	SCHEMBL12953497	0.79	MAOB (0.64)	MAOBAPPMRGPRX4TP53CYP3A4
	3-(Benzyloxy)Aniline SCHEMBL291445	0.79	MAOB (1.00)	MAOBAPPTP53CYP3A4GAA
	3-(Benzyloxy)Aniline SCHEMBL29428912	0.79	MAOB (1.00)	MAOBAPPTP53CYP3A4GAA
	SCHEMBL4639670	0.78	MAOB (0.72)	MAOBAPPTP53CYP3A4F2
	SCHEMBL4638746	0.78	MAOB (0.72)	MAOBAPPTP53CYP3A4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.