3-(Benzyloxy)Aniline

3-(Benzyloxy)Aniline

SCHEMBL291445

Nc1cccc(OCc2ccccc2)c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 1.00
APP P05067 1/20 0.72
MAOA P21397 2/20 0.63
GAA P10253 1/20 0.63
MAPT P10636 1/20 0.63
RAB9A P51151 1/20 0.63
SMN1; SMN2 Q16637 1/20 0.63
L3MBTL1 Q9Y468 1/20 0.63
BCHE P06276 3/20 0.59
CYP4F2 P78329 1/20 0.59
CYP4A11 Q02928 1/20 0.59
TP53 P04637 1/20 0.58
CYP3A4 P08684 1/20 0.58
NR4A2 P43354 1/20 0.57
ALOX5 P09917 1/20 0.56
LCK P06239 1/20 0.54
DHFR P00374 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3-(Benzyloxy)Aniline SCHEMBL29428912 1.00 MAOB (1.00) MAOBAPPMAOAGAAMAPT
3-(Benzyloxy)Aniline SCHEMBL11263814 0.98 MAOB (0.96) MAOBAPPMAOAGAAMAPT
3-(Benzyloxy)Aniline SCHEMBL28079815 0.95 MAOB (0.90) MAOBAPPMAOAGAAMAPT
3-(Benzyloxy)Aniline SCHEMBL7831693 0.92 MAOB (0.84) MAOBAPPMAOAGAAMAPT
SCHEMBL3787907 0.90 MAOB (0.81) MAOBAPPMAOAGAAMAPT
SCHEMBL2869923 0.90 MAOB (0.81) MAOBAPPMAOAGAAMAPT
SCHEMBL31114416 0.89 MAOB (0.79) MAOBAPPMAOAGAAMAPT
SCHEMBL631673 0.89 MAOB (0.79) MAOBAPPMAOAGAAMAPT
SCHEMBL1268719 0.86 MAOB (0.81) MAOBMAOABCHECYP4F2CYP4A11
SCHEMBL17064305 0.84 MAOB (0.71) MAOBAPPMAOAGAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119874601-A 3, 3-Dimethyl-1, 2,3, 4-tetrahydro-9H-carbazole derivative and preparation method and application thereof 山东大学 2025-04-25 CN claimed
CN-115710222-A Method for preparing 7-benzyloxy-4-chloroquinoline 广州康瑞泰药业有限公司 2023-02-24 CN claimed
CN-114058422-B Mannich ashless dispersant and preparation method thereof 中国石油天然气股份有限公司 2022-08-05 CN claimed
CN-114058422-A Mannich ashless dispersant and preparation method thereof 中国石油天然气股份有限公司 2022-02-18 CN claimed
CN-114057916-A Preparation method of antioxidant ashless dispersant for lubricating oil 中国石油天然气股份有限公司 2022-02-18 CN claimed
CN-111909113-A Synthesis method of 2-substituted benzothiazole compound under catalyst-free and additive-free conditions 衡阳师范学院 2020-11-10 CN claimed
EP-3037412-B1 INDOLE AMIDE COMPOUND AS INHIBITOR OF NECROSIS LG CHEMICAL LTD (KR) 2020-09-30 EP claimed
EP-1773768-B1 PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS EXELIXIS INC (US) 2018-08-22 EP claimed
US-9868731-B2 Indole amide compound as inhibitor of necrosis LG CHEM, LTD. (KR) 2018-01-16 US claimed
US-20160194313-A1 INDOLE AMIDE COMPOUND AS INHIBITOR OF NECROSIS LG LIFE SCIENCES LTD. (KR) 2016-07-07 US claimed
US-6562840-B1 Non-peptidic inhibitors of proteolytic enzymes such as urokinase 3-DIMENSIONAL PHARMACEUTICALS, INC. 2003-05-13 US claimed
WO-2003013517-A1 AMINOISOXAZOLE DERIVATIVES ACTIVE AS KINASE INHIBITORS PHARMACIA ITALIA S.P.A. (IT) 2003-02-20 WO claimed
WO-2002100822-A1 SUBSTITUTED SULFONAMIDE COMPOUNDS, PROCESS FOR THEIR USE AS MEDICAMENT FOR THE TREATMENT OF CNS DISORDERS, OBESITY AND TYPE II DIABETES BIOVITRUM AB (SE) 2002-12-19 WO claimed
US-6372030-B1 INK VEHICLE SELECTED FROM 4-(HEXADECYLAMINO)BENZYLAMINE, N-OCTANOYL-N-METHYL GLUCAMINE, OCTANOIC HYDRAZIDE, 4-HEXADECYL SULFONYL ANILINE, A CONDUCTIVE COMPLEX OF AN AMINE COMPOUND WITH A PHOSPHORUS OR SULFUR-CONTAINING ACID XEROX CORPORATION 2002-04-16 US claimed
WO-2002028353-A2 PHOSPHATE TRANSPORT INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2002-04-11 WO claimed
EP-1150979-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2001-11-07 EP claimed
US-20010031781-A1 Heteroaryl amidines, methylamidines and guanidines and use thereof as protease inhibitors ILLIG CARL R (US) 2001-10-18 US claimed
US-6291514-B1 Heteroaryl amidines, methylamidines and guanidines, preparation thereof, and use thereof as protease inhibitors 3-DIMENSIONAL PHARMACEUTICALS, INC. 2001-09-18 US claimed
WO-2000047578-A1 HETEROARYL AMIDINES, METHYLAMIDINES AND GUANIDINES AS PROTEASE INHIBITORS 3-DIMENSIONAL PHARMACEUTICALS, INC. (US) 2000-08-17 WO claimed
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160194313-A1 INDOLE AMIDE COMPOUND AS INHIBITOR OF NECROSIS IDO1, IDO2, TNF MAOB 162/4885APP 1613/4885MAOA 124/4885
US-20010031781-A1 Heteroaryl amidines, methylamidines and guanidines and use thereof as protease inhibitors SERPINE1, PRSS3, PRSS2 MAOB 628/4885APP 866/4885MAOA 610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.